FAQ: Bioidentical Hormone Replacement Therapy (BHRT) with a Naturopathic Approach

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Women's Health

Bioidentical Hormone Replacement Therapy (BHRT) is a safe and effective option for addressing hormonal imbalances in women using hormones that are chemically identical to those naturally produced by the body. In my practice as a naturopathic doctor in Ontario, I focus on transdermal options such as patches, creams, gels, and intravaginal applications for administering BHRT. This FAQ provides an overview of BHRT, covering costs, treatment duration, methods of administration, pros and cons, the ideal age to start treatment, and how it differs from traditional hormone replacement therapy (HRT).


1. What is Bioidentical Hormone Replacement Therapy (BHRT)?

BHRT uses plant-derived hormones identical to the body’s natural hormones, specifically estrogen and progesterone. This approach contrasts with traditional HRT, which often includes synthetic hormones or animal-derived hormones that are not structurally identical to human hormones. BHRT is tailored to each individual’s unique hormonal needs and has a reduced side effect profile, especially when using a balanced approach of estriol (a gentler form of estrogen) with natural progesterone.

2. How Does BHRT Differ from Traditional Hormone Replacement Therapy (HRT)?

Traditional HRT typically uses synthetic or animal-derived hormones, which may carry a higher risk of side effects such as blood clots, cardiovascular issues, and complications with breast tissue. BHRT, on the other hand, uses hormones identical to those naturally produced in the body, like estriol (a gentle form of estrogen) combined with natural progesterone, which has been shown to reduce risks associated with other forms of HRT. This approach makes BHRT both safer and more effective for alleviating hormone-related symptoms.

3. What are the Benefits of BHRT?

BHRT effectively addresses a range of symptoms associated with hormonal imbalances, including:

  • Hot flashes and night sweats
  • Mood swings, anxiety, and irritability
  • Sleep disturbances and insomnia
  • Low libido and vaginal dryness
  • Bone density loss
  • Fatigue and brain fog
  • Weight Management: Hormonal imbalances can contribute to weight gain, particularly around the abdomen, which is common during perimenopause and menopause. BHRT can help restore a balanced hormonal state, which in turn can make weight loss efforts more effective and prevent further weight gain.

Clinical evidence supports the use of BHRT for significantly reducing symptoms in women experiencing perimenopause, menopause, and hormonal fluctuations.

4. Is BHRT Safe?

Yes, BHRT is safe and effective, particularly when prescribed in bioidentical forms and carefully monitored. In my practice, I focus on estriol combined with progesterone, which greatly minimizes side effects and provides a balanced approach to hormone therapy. Research demonstrates that combining natural progesterone with estriol reduces risks associated with estrogen therapy, including those affecting breast tissue and cardiovascular health.

Estriol, in particular, is a gentler form of estrogen with a lower risk profile. When balanced with progesterone, it not only alleviates symptoms but also supports long-term health. BHRT is therefore both safe and effective when properly administered and monitored.

5. What Routes of Administration are Available for BHRT?

In Ontario, we work primarily with the following transdermal options for administering BHRT:

  • Creams and Gels: These are applied to the skin, where the hormones are absorbed into the bloodstream. Creams and gels offer flexible dosing and are easy to use.
  • Patches: Transdermal patches deliver a steady dose of hormones through the skin and are typically replaced every few days, providing consistency and convenience.
  • Intravaginal Application: Hormone creams or suppositories applied vaginally can be particularly effective for alleviating vaginal dryness and discomfort while also offering some systemic benefits.

These methods are effective and well-tolerated, providing flexibility in dosing and ease of use. I work with each patient to determine the best method based on their unique needs and lifestyle.

6. What is the Cost of BHRT?

The cost of BHRT can vary depending on the formulation and frequency of application. Here’s an overview of what you might expect:

  • Initial Consultation and Testing: $250–$600
  • Monthly BHRT Costs: $50–$200, depending on dosage and specific formulations

Some insurance plans may cover parts of the testing or follow-up consultations, though compounded bioidentical hormone formulations may not be covered. It’s always a good idea to check with your insurance provider.

7. How Long Do I Need to Be on BHRT?

The duration of BHRT depends on individual needs and goals. Some people choose to stay on BHRT long-term for symptom relief and to support overall health, while others taper off once symptoms stabilize. For some women, BHRT may only be needed for a few years during menopause, while others benefit from continued use for ongoing symptom management and prevention of hormone-related declines.

Regular check-ins help determine the most appropriate duration, and I monitor hormone levels and symptoms closely to ensure optimal dosing over time.

8. At What Age is it Ideal to Start BHRT?

BHRT can be beneficial at various stages of life, depending on hormonal needs and symptoms:

  • Perimenopause (Late 30s to Early 40s): During this phase, progesterone levels often start to decline, leading to symptoms such as mood swings, insomnia, and anxiety. Introducing bioidentical progesterone in perimenopause can help balance these symptoms early on.
  • Menopause (Typically Around 50s): BHRT can alleviate many common symptoms of menopause, including hot flashes, night sweats, and vaginal dryness.

The decision to start BHRT should be based on symptoms and hormonal testing rather than age alone. I conduct a full assessment to determine the best timing and treatment approach for each patient.

9. How Does BHRT Impact Overall Health Beyond Symptom Relief?

In addition to symptom relief, BHRT offers additional long-term health benefits:

  • Bone Health: Estrogen, especially in transdermal forms, has been shown to support bone density and reduce osteoporosis risk, making it an excellent option for women during menopause.
  • Heart Health: Studies indicate that transdermal estrogen, especially in bioidentical forms, may reduce cardiovascular risk, particularly when started in early menopause.
  • Longevity: Emerging research suggests that BHRT, particularly when initiated early in menopause, may be associated with increased longevity by supporting heart health, bone strength, and cognitive function. These protective effects collectively contribute to a reduction in overall mortality risk for women (see more).
  • Cognitive Health: Preliminary studies suggest that hormone therapy, including BHRT, may support cognitive function and reduce dementia risk when started early in menopause.

BHRT’s benefits extend beyond symptom relief, and I assess each patient’s health history and goals to create a plan that supports long-term wellness.

10. Does BHRT Interact with Other Medications or Supplements?

Estrogen and progesterone in bioidentical forms generally have a lower interaction risk compared to synthetic hormones; however, interactions are possible. Certain medications and supplements can affect how hormones are metabolized, potentially altering the effectiveness or required dosage of BHRT. For example, medications that induce liver enzymes may speed up hormone metabolism, while some herbal supplements could have mild estrogenic effects that influence the overall hormonal balance.

When prescribing BHRT, I review all medications and supplements a patient is currently using to ensure compatibility and reduce the risk of interactions. Regular monitoring and communication are essential to maintaining safe and effective hormone levels.

11. Is BHRT Right for Me?

BHRT is a powerful option for individuals experiencing symptoms related to hormonal imbalances or age-related hormonal declines. However, it is not a one-size-fits-all solution. I work closely with each patient to develop a personalized approach that involves thorough testing, regular monitoring, and dose adjustments to ensure a safe and effective experience with BHRT.


Bioidentical Hormone Replacement Therapy offers a natural, effective way to manage hormonal imbalances and alleviate symptoms associated with perimenopause, menopause, and related life stages. As a naturopathic doctor, I focus on safe, transdermal routes that reduce side effects and provide a balanced approach to hormone health.

If you’re considering BHRT, I’m here to guide you through testing, hormone selection, and dosing options for a safe and effective treatment tailored to your unique needs.

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